Pulis Group
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PhD funded by EPSRC DLA available:
Accessing deuterated amine-based pharmaceuticals through new approaches to hydrogen isotope exchange
Get in touch with Alex for informal enquiries
Further information here and here
Closing date: 6th Feb 2026

welcome to the Pulis Group website.

Our research discovers fundamental reactivity and applies it to solve problems in biology.

news.

Follow @PulisGroup

10/2025  Happy Halloween! 🎃 
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10/2025  Welcome to the group, Simone (PhD).

10/2025  Sophia and Yuncong attended the Sygnature Discovery Medicinal Chemistry Workshop.

09/2025  Welcome to the team Jacob (PhD), Yanjia (PhD) and Zain (MChem).
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09/2025  Sophia presented her research at the 39th Postgraduate Symposium of the RSC Heterocyclic & Synthesis Group at the University of Oxford as an oral talk.

07/2025  Happy to share our latest work on B(C6F5)3-Catalyzed Tetrahydroquinolines synthesis from N-Alkyl Arylamines and Alkenes. Congratulations to the group!

07/2025  We had a fantastic day at the School of Chemistry Research Symposium where Sophia gave an oral presentation and Yuncong presented his poster.
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05/2025  Pulis group and Stuart group succeeded escaping the wizard secret room.
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04/2025  Yuncong Gao gave a poster presentation in RSC Organic Community Midlands Regional Meeting at ​Nottingham. 
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04/2025  Pulis group attended the Bristol Synthesis Meeting 2025​. What a lovely day! (especially the after meeting activities)

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02/2025  The Pulis Group visit Alex's mother land without Alex.
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12/2024  Joe presents his poster at the RSC Organic Chemistry Poster Symposium 2024. Well done Joe. (Alex tags along for fun)

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11/2024  We have a new Doctor in the house. Congratulations to Dr. Joseph P. Gillions!
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11/2024  Alex gave invited lectures at Shanghai Institute of Organic Chemistry and ShanghaiTech. Thank you Huan-ming and Fanke for being excellent hosts.
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10/2024  Welcome our new MChem student Josh Barkus.
And Happy Halloween!
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10/2024  Sophia gave an oral presentation at the 2024 GSK Synthetic Organic Chemistry Postgraduate Symposium.

09/2024  Sophia attended the Charles River Poster Competition.

09/2024  Sophia presents a flash and poster presentation at the 38th Postgraduate Symposium of the RSC Heterocyclic & Synthesis Group at the University of Edinburgh.
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07/2024  Our group attended the 2024 Oxford Synthesis Summer Conference in the University of Oxford​. ​Sophia gave a flash presentation. Lei and Sophia gave poster presentations.
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07/2024  Our very own Laura Winfrey (PhD student) and Ceri Rees (MChem student) graduates.
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Ceri was camera shy so we didn't manage to get a photo of him on his big day.
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07/2024  Joe gave an oral presentation at the International Society of Heterocyclic Chemistry Congress 2024.
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07/2024  Alex takes his group for a walk at Bradgate Park
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07/2024  Lei gave an oral presentation and Sophia presented a poster at The School of Chemistry Research Symposium.
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06/2024  Sophia attends the 2nd EWOC Europe Conference at Birmingham and presents a poster.
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06/2024  Alex talks at the New Starters in Synthesis and Catalysis 2024, at Imperial College London.

04/2024  Our group attended the RSC Organic Community Midlands Regional Meeting at Keele University​. ​Alex gave an oral presentation. Joe, Sophia and Lei gave poster presentations and Sophia won the poster prize. Congratulations! 
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04/2024  Our group attended the Bristol Synthesis Meeting 2024​.
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04/2024  Sophia won the oral presentation prize at the RSC Fluorine Interest Group Postgraduate Meeting. Congratulations! ​
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04/2024  A big warm welcome to our new Postdoc, Masha.
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03/2024  Our paper on the B(C6F5)3 catalyzed dehydrogenation of pyrrolidines has been accepted in ACS Catalysis. Well done Ana, Joe, Laura, and Yukang. It was great to collaborate with Dr Yang Li at Dalian University of Technology.
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03/2024  Alex presents at DSTL, Porton Down.​

02/2024  Alex presents at GSK in Stevenage for an Emerging Academics Seminar.​

01/2024  Alex has received a Thieme Chemistry Journal Award for 2024.​

01/2024  After a great collaboration with Rama Suntharalingam, our paper 'H2O·B(C6F5)3-Catalyzed para-Alkylation of Anilines with Alkenes Applied to Late-Stage Functionalization of Non-Steroidal Anti-Inflammatory Drugs' has been published Chemistry A European Journal. Well done Laura, Lei, and Ginevra. link
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11/2023  Alex gives seminars at Dalian University of Technology and Nankai University.  
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With Dr Fei Wang outside the State Key Laboratory of Elemento-Organic Chemistry, Nankai University
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With Dr Yang Li and her group at DUT
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09/2023  Lei and Sophia attended the 37th Postgraduate Symposium run by the RSC Heterocyclic & Synthesis Group. Lei presented a poster and gave an oral presentation.
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07/2023  Joe presents a poster at 27th International symposium: Synthesis in organic chemistry. 

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07/2023  
Congratulations! PhD student Ana Alvarez Montoya graduates. 
MChem students
Liam Neligan and Halima Patel graduate. 
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06/2023  Joe gave a oral presentation and Lei presented a poster in the Leicester symposium day.

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06/2023  Laura and Sophia attend Empowering Women in Organic Chemistry Europe;
Laura presented a poster at this conference.

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06/2023  Our review on organoborane mediated hydride abstraction is out in Synlett. Well done Joe, Laura, and Lei. Great collaborating again with the Morrill and Melen groups in Cardiff.

Invited contribution to celebrate 60 years of Donald Matterson’s boron homologation
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Recent Advances in Catalysis using Organoborane Mediated Hydride Abstraction
Synlett 2023, DOI:10.1055/a-2111-9629
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05/2023  Dr Alex Pulis gave a talk and Laura Winfrey won the oral presentation prize at 25th Lakeland Symposium (Grasmere) 2023.
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04/2023  Dr Alex Pulis, Laura Winfrey, Joseph Gillions, Lei Yun and Sophia Moreen Gloria attended Bristol Synthesis Meeting 2023.
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10/2022  Welcome Halima and Liam, our new MChem students. We also welcome a new PhD student Sophia from University of Leicester.
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10/2022  Laura Winfrey gave a flash talk and poster presentation at GSK Synthetic Organic Postgraduate Symposium 2022.

09/2022  Laura Winfrey gave a poster presentation at NWO Chains Conference 2022 in Veldhoven, Netherlands.
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07/2022  Laura Winfrey goes to the Slootweg research group in Amsterdam with the Turing Scheme 2022.
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06/2022  Joe Gillions is the winner of the poster competition during the UoL PG Chemistry Research Day.
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05/2022  Alex gave a talk at the Keele Chemical Sciences Symposium​.
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03/2022  Laura Winfrey gave a poster presentation at Charles River PhD Poster Competition 2022​.
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10/2021  Welcome Sophia and Haris, our new MChem students. We also welcome a new PhD student Lei from Dalian University of Technology.

03/2021  Our review on borane mediated hydride abstraction is out in Chem. Soc. Rev. Well done Shyam, Laura, and Betty. Great collaborating again with the Morrill and Melen groups in Cardiff.
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Electron deficient borane-mediated hydride abstraction in amines: stoichiometric and catalytic processes
Chem. Soc. Rev. 2021, DOI: 10.1039/D0CS00531B
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10/2020  The group welcomes our new MChem project student, Anthony. We also welcome a new PhD student Joe from the University of York.
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04/2020  Our first research paper from Leicester is out in ACS Catalysis! Well done Shyam, Ana, and Laura. Great Collaboration with the Morrill and Melen groups in Cardiff.

B(C6F5)3-Catalyzed Direct C3 Alkylation of Indoles and Oxindoles

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​01/2020  Our review on FLPs is out!  Well done Laura and Ana.

Uncovering the Synthetic Potential of Frustrated Lewis Pairs
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09/2019  The group welcomes several new members: Our new MChem project students, Amy Shah and Tom Arkley; Laura Winfrey to start her PhD; and Djawid Mohammadi from Hamburg for his Masters project. Welcome!

06/2019  Laura Winfrey (MChem project student) presents at the SCI Undergraduate Research Symposium at Imperial College London.
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06/2019  Alex publishes in ACS catalysis with Prof. Procter, Tao Jia, Marshall Smith and Gregory Perry

Enantioselective and Regioselective Copper-Catalyzed Borocyanation of 1-Aryl-1,3-Butadienes
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05/2019  We welcome to Zhiming Yang (Steve) into the group for his MSc project.

04/2019  The group has been awarded a Royal Society Research Grant!
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04/2019  We welcome to Antoine, an Erasmus student from the Universite de Rouen, (France).

04/2019  Alex publishes in Angew. Chem. Int. Ed.  with Prof. Procter, Mindaugas Šiaučiulis and Nanna Ahlsten 

Transition metal‐free cross‐coupling of benzothiophenes and styrenes in a stereoselective synthesis of substituted (E,Z)‐1,3‐dienes


​and with Zhen He

The interrupted Pummerer reaction in a sulfoxide‐catalyzed oxidative coupling of 2‐naphthols


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01/2019  A huge welcome to Ana, the groups first PhD student! Ana Alvarez Montoya is from Universidad de Oviedo (Spain).

01/2019  Alex publishes in ACS Catalysis with Prof. Procter, Kay Yeung, Fabien Talbot and Gareth Howell

Copper-catalyzed borylative multi-component synthesis of quaternary α-amino esters
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11/2018  Alex publishes in Org. Lett. with Prof. Procter , Kevin Yang and Greg Perry.

Transition-Metal-Free Synthesis of C3-Arylated Benzofurans from Benzothiophenes and Phenols

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09/2018  Research starts at The University of Leicester!

It has been a great experience at the University of Manchester. A big thank your to Prof. Procter, and his fantastic research group.
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07/2018  Alex publishes in Angew. Chem. Int. Ed.  with Prof. Procter, Tao Jia, Qiong He (Jessica), and Rebecca E. Ruscoe.
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Regiodivergent copper catalyzed borocyanation of 1,3-dienes
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06/2018  Alex publishes in Angew. Chem. Int. Ed.  with Prof. Procter, Miles H. Aukland, Fabien J. T. Talbot, José A. Fernández-Salas, and Matthew Ball.
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An Interrupted Pummerer/Nickel‐Catalysed Cross‐Coupling Sequence

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05/2018  As we say farewell to an excellent bunch of MChem students (Yasmin and Lucy), we welcome Adrien (Erasmus, Universite de Rouen, France) and Suki (MSc Taught project) for the summer.

03/2018  Alex publishes in Angew. Chem. Int. Ed.  with Prof. Procter, Zhen He, Harry J. Shrives, José A. Fernández-Salas, Alberto Abengózar and Jessica Neufeld
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Synthesis of C2 Substituted Benzothiophenes via an Interrupted Pummerer/[3,3]-Sigmatropic/1,2-Migration Cascade of Benzothiophene S-Oxides
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11/2017  Alex publishes in Chem. Sci. with Prof. Procter, Mindaugas Šiaučiulis and Selma Sapmaz.

Dual vicinal functionalisation of heterocycles via an interrupted Pummerer coupling/[3,3]-sigmatropic rearrangement cascade
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08/2017  Luke, Hassan and Alex publish in Chem. Commun. Well done Luke!

One-pot borylation/Suzuki-Miyaura sp2–sp3 cross-coupling  
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  • home
  • our research
  • the group
  • publications
  • contact
  • group pictures
    • pics around the lab
  • useful links